• Search
  • Contact Us
  • Blogs
  • Healthcare Professionals
    • Blogs
      • Expand OAB Care
      • Sterile Endoscopy
    • Specialties
      • Urology
      • Endourology
      • Gynecology
      • Bariatric Medicine
      • Critical Care
      • Gastroenterology
      • Infection Prevention
      • Otolaryngology
      • Pulmonology
      • Senior Living
    • Products
      • PrimeSight
        • Clinical Data
        • Flexible Endoscopes
        • Rigid Endoscopes
        • Video System
        • Light Sources
        • Accessories
      • EndoSheath
        • Clinical Data
      • Urgent PC
        • Clinical Data
      • Macroplastique
        • Clinical Data
    • Reimbursement
      • Urgent PC
        • Coverage Finder
        • Prior Auth
        • Appeals
      • Macroplastique
        • Prior Auth
        • Appeals
      • Endoscopy
    • Upcoming Meetings
    • Resource Center
  • Patients
    • Conditions
      • Overactive Bladder
      • Stress Urinary Incontinence
    • Endoscope Safety
    • Products
      • PrimeSight
      • Macroplastique
        • Stories
      • Urgent PC
        • Stories
    • Resource Center
    • MyPTNS
  • Customer Care
    • Product Ordering
      • Ordering Questions
      • New Account Form
      • Service Plans
      • Terms and Conditions
    • Repair and Support
      • Technical Support Questions
      • Returns and Feedback
        • Incident Report
      • Product Instructions
    • Contact Customer Care
  • About Us
    • Locations
    • History
    • Affiliations
    • Careers
      • Available Positions
Cogentix Medical
Menu

Pilot randomized crossover study comparing the efficacy of transnasal disposable Endosheath with standard endoscopy to detect Barrett's esophagus.

Shariff, M.K., Varghese, S., O'Donovan, M., Abdullahi, Z., Liu, X., Fitzgerald, R.C., & di Pietro, M. (2016). Endoscopy, 48(2), 110-6.
Abstract
BACKGROUND AND STUDY AIMS:

The transnasal endosheath endoscope is a new disposable technology with potential applicability to the primary care setting. The aim of this study was to evaluate the efficacy of transnasal endosheath endoscopy (TEE) for the detection of Barrett's esophagus, by comparing the diagnostic accuracy of TEE with that of standard endoscopy.

PATIENTS AND METHODS:

This was a prospective, randomized, crossover study performed in a single tertiary referral center. Consecutive patients undergoing surveillance for Barrett's esophagus or referred for diagnostic assessment were recruited. All patients were randomized to undergo TEE followed by standard endoscopy or the reverse. Endoscopy experiences and patient preferences were evaluated using a questionnaire. Endoscopic and histologic diagnosis of Barrett's esophagus, and optical image quality of both endoscopic procedures, were compared.

RESULTS:

A total of 21 of 25 patients completed the study. TEE had sensitivity and specificity of 100 % for an endoscopic diagnosis of Barrett's esophagus, and of 66.7 % and 100 %, respectively, for the histologic diagnosis of Barrett's esophagus. The mean optical quality of standard endoscopy was significantly better than that of TEE (7.11 ± 0.42 vs. 4.06 ± 0.27; P < 0.0001). However, following endoscopy, patients reported a significantly better experience with TEE compared with standard endoscopy (7.05 ± 0.49 vs. 4.35 ± 0.53; P = 0.0006), with 60 % preferring TEE and 25 % preferring sedated standard endoscopy.

CONCLUSIONS:

In this study, TEE had equal accuracy for an endoscopic diagnosis of Barrett's esophagus compared with standard endoscopy, at the expense of reduced image quality and a lower yield of intestinal metaplasia on biopsy. TEE was better tolerated and preferred by patients. Hence, TEE needs further evaluation in primary care as an initial diagnostic tool.

© Georg Thieme Verlag KG Stuttgart · New York.

  • Twitter
  • Facebook
  • YouTube
  • Contact Us
  • Terms of Use
  • Privacy Center
© 2021 Cogentix Medical. Some Cogentix Medical products may not be available in certain regions.

What can we help you with?

  • Customer Care
  • Expert Information