de la Portilla, F., et al. (2009). Dis Colon Rectum, 52(8), 1427-33.
PURPOSE: Neuromodulation therapies have been used with success in patients with fecal incontinence. Intermittent percutaneous tibial nerve stimulation is a new, minimally invasive treatment option for these patients. This study was designed to evaluate the results of intermittent percutaneous tibial nerve stimulation in patients with fecal incontinence.
METHODS: Sixteen patients (11 females; mean age, 59 ± 7.9 years) with severe fecal incontinence were treated with percutaneous tibial nerve stimulation. All patients completed a defecation diary, the Wexner Fecal Continence Scale, a fecal incontinence quality-of-life questionnaire, and a visual analog scale before treatment and during each phase of the study. Endoluminal ultrasound and anorectal physiologic studies were also performed in each patient.
RESULTS: Continence was improved in 10 of 16 patients after the first phase. Six patients did not continue to the second phase of treatment because of a lack of initial response. During the second phase, 7 of 16 continued to show improvement. After a six-month period without any treatment, 5 of 16 continued to have good continence. Overall, percutaneous tibial nerve stimulation significantly improved fecal continence. The Wexner score improved from a mean of 13.2 ± 4.1 at baseline to 9 ± 5.2 at the end of the first phase (P < 0.0005), to 8 ± 5.7 at the end of the second phase (P = 0.001), and to 9.1 ± 5 after 6 months without treatment (P = 0.001). Significant improvement was observed in three main domains of the fecal incontinence quality-of-life scale: coping/behavior, depression, and embarrassment. Scores on the visual analog scale improved from a mean of 4.6 ± 1.5 at baseline to 7 ± 2.5 at the end of the first phase (P = 0.002) and to 7.2 ± 2.5 after 6 months without treatment (P = 0.001).
CONCLUSION: Percutaneous tibial nerve stimulation is a minimally invasive and effective treatment option for patients with fecal incontinence.
Source: PubMed 19617756