PTQ® Clinical Data
Clinical trials have demonstrated that PTQ Implants result in substantial improvement in faecal continence and quality of life in patients with internal sphincter dysfunction - without the risk of complications inherent in the use of more invasive surgical procedures.
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Injectable silicone biomaterial (PTQ™) is more effective than carbon-coated beads (Durasphere®) in treating passive faecal incontinence - a randomized trial.
Tjandra, J.J, et al (2009). Colorect Dis, 11, 382-389.
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Evaluation of the use of PTQ™ implants for the treatment of incontinent patients due to internal anal sphincter dysfunction.
de la Portilla, F., et al. (2008). Colorect Dis, 10(1), 89-94.
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Anal incontinence improvement after silicone injection may be related to restoration of sphincter asymmetry.
Oliveira, L., et al. (2008). Colorect Dis, 10(Suppl 2), 16, 19.
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Managing faecal incontinence: The role of PTQ injections.
Gett, R.M., et al. (2007). ANZJ Surg, 77(Suppl 1), A16.
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Efficacy of the agent PTQ in the treatment of faecal incontinence.
Gaj, F., et al (2007). Chir Ital, 59(3), 355-359.
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PTQ™ Implants in the treatment of faecal soiling.
van der Hagen, S.J. et al (2007). British Journal of Surgery, 94, 222-223.
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Injectable silicone biomaterial (PTQ) to treat fecal incontinence after hemorrhoidectomy.
Chan, M.K., et al. (2006). Dis Colon Rectum, 49(4), 433-439.
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Long-term results of injectable silicone biomaterial for passive fecal incontinence: A randomized trial.
Tjandra, J.J., et al.(2006). Dis Colon Rectum, 49(5), 730-731.
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Implantable Silicone for Passive Fecal Incontinence Secondary to Internal Anal Sphincter Deficiency.
Bach, S., et al. (2004). Presented at ASCRS, Dallas, TX, May 2004.
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Injectable silicone biomaterial for fecal incontinence caused by internal anal sphincter dysfunction is effective.
Tjandra, J.J., et al. (2004). Dis Colon Rectum, 47(12), 2138-2146.
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Injectable silicone biomaterial for faecal incontinence due to internal anal sphincter dysfunction.
Kenefick, N.J., et al. (2002). Gut, 51(2), 225-228.
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Internal anal sphincter augmentation for fecal incontinence using injectable silicone biomaterial.
Malouf, A.J., et al. (2001). Dis Colon Rectum, 44(4), 595-600.
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PTQ anal implants for the treatment of faecal incontinence.
Bartlett, L., et al. (2009). Br J Surg, 96(12), 1468-75.
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Anal incontinence improvement after silicone injection may be related to restoration of sphincter asymmetry.
Oliveira, L.C.C., et al. (2009). Surg Innov, 16, 155-161.
