OBJECTIVE: To evaluate the long-term efficacy of endoscopic injection of Macroplastique (Polydimethylsiloxane, PDMS) in male and female Urinary Incontinence (UI).
Patients and Methods: A total of 87 patients with different causes of urinary Incontinence have been treated by endoscopic injection of PDMS at our department between 1997 and 2001. The group consisted of 39 male and 48 female patients with a mean age of 58 and 44 years, respectively. All patients underwent a sophisticated history taking including Urodynamics and were instructed to complete a pre and postoperative voiding diary. The results were evaluated by questionnaire at 1, 6, 12 and 24 months after injection. The outcome was classified as dry in all circumstances, improved or failed.
RESULTS: At one month, 5 male (13%) and 10 female (21 %) patients were dry, while 27 males and 29 females had improved and treatment had failed in 7 males (18%) and 9 females (19%). At the last followup (mean injections = 2,5), 12 males patients (31%) and 27 female patients (56%) were classified as dry, 18 males (46%) and 14 females (29%) were improved, while in 9 males (23%) and 7 females (15%) the procedure had failed, The overall success rate (dry and improved) was 77% for the males and 85% for the females.
CONCLUSION: The use of PDMS (Macroplastique) is a good and effective alternativefor the treatment of intrinsic sphincter deficiency in male and female patients. The implants do not lose volume over time and havea good long-term effect.
Source: Original Abstract